- Supply
- 45 g / stated three months
- Price
- $50/month equivalent; $150 per stated interval
- Named active
- Estriol
One M4 product, not the whole range
The selected M4 Face Cream Rx is described as an estriol-containing, fragrance-free face cream. The eye cream and serum are separate products. The provider says a clinician reviews an intake before prescribing.[source]
Check that the proposed item matches the research and instructions being discussed. A result involving one formulation should not be assumed to describe a bundle or a different application area.
Provider-reported findings require context
Alloy advertises a 12-week placebo comparison with changes in elasticity, hydration and other measures. It also says the product does not affect blood estrogen levels.[source]
We have not independently established that these statements demonstrate zero exposure under every usage condition. Ask the prescriber how the evidence applies to your medical history, dose and other hormone treatment. A clinical study claim is not the same regulatory fact as an approved estriol drug; FDA says there are none.[source]
Price the actual delivery interval
The offer is one 45 g bottle billed on a three-month subscription at a $50 monthly equivalent. That is $150 for the stated interval before any applicable adjustments. The page describes the intake review as free.[source]
Confirm the renewal date and support pathway rather than assuming all Alloy care is included. This option may be worth discussing within menopause-focused care, but a facial prescription should not be used as a self-directed substitute for treatment of systemic symptoms or as a reason to change an existing hormone regimen.
Sources & further reading
Provider pages establish what a brand markets. Clinical and regulatory sources establish the limits of the evidence. Accessed October 8, 2026.
- Alloy: M4 Face Cream RxOfficial source; checked October 8, 2026
- FDA: menopause and hormone questionsNo FDA-approved estriol drugs; compounded does not establish superior safety